Pregnancy in Functional and Integrative MedicineE-book · Supplementation, formulas and guidance
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Cover of the e-book Pregnancy in Functional and Integrative Medicine: advanced supplementation, compounded formulas and pregnancy guidance.Coming soon

PDF e-book · 97 pages · Dr. Estela Reginatto

Pregnancy in Functional and
Integrative Medicine

A pregnant woman who swaps table salt for pink salt and cuts out ultra-processed foods may, without noticing, cut out her main source of iodine, precisely when her need rises to 220 mcg a day and the baby's brain depends on the mother's thyroid hormone. At the other extreme, a single drop of 5% Lugol's solution contains almost 30 times that need. This e-book shows where the "healthy" pregnancy goes wrong and delivers the fine-tuning: active forms, doses by trimester, 22 compounded formulas and Dr. Estela's guidance.

  • Advanced supplementation: the right active form, dose and timing
  • 22 compounded formulas, from preconception to breastfeeding
  • Pregnancy guidance: food, a toxin-free home and sleep

The English edition is coming soon

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Tap "Notify me" and send the ready-made WhatsApp message: we will let you know when the English edition is out.
For pregnant women, women trying to conceive and breastfeeding mothers, and for health professionals.

01Why this e-book exists

What almost no one tells you
about supplementation in pregnancy.

Between the pharmacy multivitamin and tips from social media, pregnancy is usually managed by the bare minimum. These are six points the e-book takes apart, each with the studies that support it and the module where the topic is covered in detail.

  • 01Modules 5 and 20

    "Swapping table salt for pink salt is always healthier"

    In pregnancy, it may not be. In Brazil, iodized salt is the main source of iodine, and many specialty and imported salts are not iodized. A woman who switches salt, cuts out ultra-processed foods and eats little fish and dairy can fall well below 220 mcg of iodine a day without noticing. In São Paulo, 57% of the pregnant women assessed were below the adequate level.

  • 02Module 5

    "Lugol's iodine raises the baby's IQ"

    Iodine protects the baby's brain, but in micrograms. One drop of 5% Lugol's solution contains about 6,300 mcg of iodine, almost 6 times the tolerable upper intake level, and three babies with congenital hypothyroidism have been described whose mothers took 12.5 mg a day during pregnancy or breastfeeding, the equivalent of two drops. The e-book provides the formula for Lugol's diluted to 50 mcg per drop.

  • 03Modules 2 and 4

    "Folic acid starts when the test comes back positive"

    The neural tube closes between the 21st and 28th day after conception, when many women do not even know they are pregnant yet. And stores take time: after 24 weeks of supplementation, red blood cell folate had still not reached a plateau. That is why the e-book's protocol starts three to six months before, together with vitamin B12.

  • 04Modules 6 and 7

    "The prenatal multivitamin already has everything"

    Almost none provides enough choline and DHA. Choline is required in amounts hundreds of times greater than folate, and in the United States only 8.5% of pregnant women reach the recommendation. In the Cornell trial, the babies of mothers who received 930 mg a day had faster reaction times, a marker of processing speed.

  • 05Modules 9 and 14

    "Iron in pregnancy: the more, the better"

    Iron prevents anemia, but in excess it raises hemoglobin above the ideal. In a cohort of 278 children, those born with the lowest cord ferritin performed worse at age 5, and those with the highest were more likely to have a low IQ. In the e-book, the dose comes from ferritin, and intravenous iron comes with indications, dose calculation and drip rate.

  • 06Module 20

    "One small coffee a day does no harm"

    Caffeine crosses the placenta, and the fetus lacks the enzymes to metabolize it. Traditional guidelines accept up to 200 mg a day, but a review of 48 studies concluded that pregnant women and women planning to conceive should avoid it, and in two American cohorts even low intakes were associated with shorter children in childhood.

The e-book does not replace prenatal care or a consultation. All supplementation is individualized, prescribed by a licensed professional and reported to the obstetrician, and what is the author's clinical practice is marked [PA], kept apart from what is backed by studies.

02What you get

From preconception to postpartum,
with the evidence for each step.

The terms of the cover subtitle, delivered as dose tables, formulas and guidance for everyday life.

The functional view of pregnancy

Conventional medicine asks: "is there a deficiency or a disease?". Functional medicine asks: "does this body have everything it needs to function optimally, and what is getting in the way?". In pregnancy, this means moving beyond the minimum needed to avoid disease (the laboratory reference value) and seeking the optimum to build a healthy baby and preserve the mother's health.

How the boxes appear in the e-book (module 1)
01
Parts 1 and 2 · modules 2 to 10

Advanced supplementation: the form, the dose and the timing of each nutrient

It is not "a prenatal multivitamin": it means starting from lab tests, choosing the most bioavailable form and adjusting the dose throughout the trimesters.

  • Active folate (5-MTHF) and methylcobalamin, the MTHFR variant and homocysteine as a gauge of methylation
  • Iodine and IQ: what each study showed, unrefined salt and the dose of 150 mcg a day
  • Choline and DHA: the Cornell study and the ADORE trial, in which high-dose DHA reduced early preterm birth, especially in pregnant women with low DHA
  • Vitamin D with a target of 40 to 60 ng/mL, iron guided by ferritin and the author's functional lab panel
  • Nutraceuticals with clinical trials in pregnancy: myo-inositol, coenzyme Q10, L-arginine, lactoferrin and strain-specific probiotics
02
Part 3 · modules 11 to 19

22 compounded formulas and supplementation by goal

Each formula with composition, dosage and indication, and each goal with the approach and the warning signs.

  • The preconception formula, the active methylation formula and the functional prenatal multivitamin for the 2nd and 3rd trimesters
  • Pregnancy Lugol's diluted to 50 mcg per drop, to deliver micrograms and not milligrams
  • Formulas for nausea, gestational diabetes, preeclampsia, anemia, thyroid, allergies, constipation and cramps
  • The supplementation calendar by trimester and the daily schedule, from breakfast to bedtime
  • Intravenous iron when the oral route is not enough: indications, contraindications, Ganzoni formula, dilution and drip rate
03
Parts 4 and 5 · modules 20 to 26

Pregnancy guidance: the routine Dr. Estela gives in her practice

Food, home, sleep and emotions, product by product and hour by hour.

  • The daily goals: protein at every meal, 2 to 2.5 liters of water, zero sugar and zero coffee
  • Low-mercury fish, the right salt, the fats for cooking and a 7-day menu with 9 recipes
  • A home with fewer toxins in 10 steps: cookware, cosmetics, perfume, cleaning products and insect repellent
  • Sleep before 10 p.m., sunlight, movement and reading aloud: newborns recognize the story they heard in the womb
  • Postpartum and breastfeeding, pregnancy month by month and 6 application profiles for professionals
03Contents

97 pages in five parts.

From the foundations to the pregnant woman's routine: the preconception window and lab tests, the nutrients that build the baby, supplementation by goal with the compounding formulary, pregnancy guidance and a supplement with the postpartum period, pregnancy month by month, frequently asked questions and a glossary. Studies are numbered, and the author's practice is marked [PA].

Part 1

Foundations

Pregnancy from a functional perspective, the preconception window and the lab tests that guide supplementation.

  1. Mod. 1Pregnancy from a functional perspective
  2. Mod. 2The preconception window: preparing the ground before conceiving
  3. Mod. 3Functional lab tests in pregnancy and preconception

Part 2

Nutrients That Build the Baby

Active folate and B12, iodine, choline, DHA, vitamin D, the minerals of fetal development and advanced nutraceuticals.

  1. Mod. 4Folate and vitamin B12: neural tube, methylation and the active forms
  2. Mod. 5Iodine: the baby's thyroid and IQ
  3. Mod. 6Choline: the forgotten nutrient of the fetal brain
  4. Mod. 7Omega-3 DHA: brain, retina and birth at the right time
  5. Mod. 8Vitamin D: the solar hormone of pregnancy
  6. Mod. 9Minerals and vitamins of fetal development
  7. Mod. 10Advanced nutraceuticals and research frontiers

Part 3

Supplementation by Goal

Integrative strategies and compounded formulas for each stage and each challenge of pregnancy.

  1. Mod. 11Nausea, vomiting and hyperemesis
  2. Mod. 12Gestational diabetes and insulin resistance
  3. Mod. 13Preeclampsia and gestational hypertension
  4. Mod. 14Anemia and iron stores
  5. Mod. 15Thyroid in pregnancy
  6. Mod. 16Microbiota, immunity and allergy prevention
  7. Mod. 17Common discomforts: from the gut to preparing for birth
  8. Mod. 18Pregnancy compounding formulary
  9. Mod. 19What to avoid: supplements, plants, drugs and habits

Part 4

Pregnancy Guidance

Food, a toxin-free environment, sleep, emotions and the bond that begins in the womb.

  1. Mod. 20Functional nutrition in pregnancy
  2. Mod. 21A toxin-free environment
  3. Mod. 22Sleep, sunlight, movement, emotions and the bond in the womb
  4. Mod. 23Functional 7-day menu and pregnancy recipes

Part 5

Advanced Supplement

Postpartum and breastfeeding, pregnancy month by month, application profiles, frequently asked questions, glossary and references.

  1. Mod. 24Postpartum and breastfeeding: the fourth trimester
  2. Mod. 25Pregnancy month by month: what forms and what to nourish
  3. Mod. 26Application profiles: functional reasoning in practice
  4. Mod. 27Frequently asked questions
  5. Mod. 28Glossary of acronyms and terms
  6. Mod. 29References

Evidence tags · Table 2

[MA]
Meta-analysis or systematic review (includes Cochrane)
[ECR]
Randomized controlled trial
[OBS]
Observational study (cohort, case-control)
[EXP]
Experimental study in animals or in the laboratory
[CL]
Consensus, guideline or position of a scientific society
[PA]
The author's clinical practice
05Who it's for

Written for those who are pregnant and for those who care for the pregnancy.

The e-book was written for pregnant women, women trying to conceive and breastfeeding mothers and their families, and for health professionals. The pregnant woman understands what is happening in her own body and in the baby's and arrives at her appointment knowing what to ask; the professional finds doses, forms, formulas and references, within the legal limits of their profession.

Pregnant women, women trying to conceive and breastfeeding mothers

And their families, who want to understand each stage and talk about it with the team that cares for the pregnancy.

  • Why folate and B12 start three to six months before, and what to do if you are already pregnant
  • What to check on the multivitamin label: active folate, 150 mcg of iodine and vitamin A as beta-carotene
  • What to avoid, from plants and teas to cosmetics and hair dyes, and the warning signs that call for immediate care
  • The author's routine: 7-day menu, recipes, sleep, sunlight, movement and reading aloud to the baby

Health professionals

Nutritionists, physicians, biomedical scientists, pharmacists and obstetric nurses, as a reference work, within the legal limits of each profession.

  • The functional lab panel with the author's ranges and the reassessment calendar by trimester
  • The 22 compounded formulas with composition, dosage and the daily totals to check before combining
  • Approaches by goal: nausea, gestational diabetes, preeclampsia, anemia, Hashimoto's and allergies
  • Intravenous iron, from indications to managing reactions, and 6 application profiles of functional reasoning

For pregnant women and families, the e-book is material for understanding: it is not a prescription, it does not replace prenatal care or a consultation with a licensed professional, and no medication in use should be stopped or changed on your own.

06Offer

The complete e-book
coming soon in English.

The English edition is in preparation. Leave your request and we will message you on WhatsApp when it launches.

Cover of the e-book Pregnancy in Functional and Integrative Medicine: advanced supplementation, compounded formulas and pregnancy guidance.Coming soon

AuthorDr. Estela Reginatto@nutri.estela.reginattoOctober 2026 edition

What you get
  • A 97-page PDF e-book with 29 modules in 5 parts
  • From preconception to postpartum: the preconception window, functional lab tests and pregnancy month by month
  • Active folate and B12, iodine, choline, DHA, vitamin D, minerals and nutraceuticals, with doses by trimester
  • 22 compounded formulas, the supplementation calendar and the daily schedule
  • Nausea, gestational diabetes, preeclampsia, anemia and intravenous iron, thyroid, microbiota and discomforts
  • Functional nutrition, a home with fewer toxins, sleep and bonding, a 7-day menu and 9 recipes
  • 51 tables, 116 scientific references, 19 frequently asked questions and a glossary of acronyms and terms
PDF pages
97
modules in 5 parts
29
compounded formulas
22
tables
51
scientific references
116

Studies are numbered in the text, with title and link in Module 29, and the author's clinical practice is marked [PA], kept apart from what is backed by studies. In the "Critical reading" boxes, the e-book shows what each study allows us to state and where it stops.

The English edition is coming soon

Notify me

Tap "Notify me" and send the ready-made WhatsApp message: we will let you know when the English edition is out.

07FAQ

Frequently asked
questions

If yours is not here, write to contato@basefuncional.com.

08Who's behind it
Dr. Estela Reginatto
Partner

Dr. Estela Reginatto

@nutri.estela.reginatto

Clinical nutritionist, specialist in functional medicine and nutrition.

She has a strong focus on pregnancy, weight loss and clinical nutrition for disease. In pregnancy, she nourishes the mother's health and the baby's development. In weight loss, she goes beyond the scale and treats the cause: metabolism, hormones and the gut. In established diseases, she makes food part of the treatment. In hormonal and thyroid health, she combines functional nutrition with herbal medicine.

She holds a postgraduate degree in Nutritional Adequacy and Maintenance of Endocrine Homeostasis: Prevention and Treatment of Age-Related Diseases, with Dr. Lair Ribeiro. She also holds postgraduate degrees in Phytotherapy and in Food Quality Management.

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From the first folate to postpartum,
a pregnancy nourished with dose and evidence.

Notify me

97 pages, 29 modules and 22 compounded formulas, coming soon in English.

For pregnant women, women trying to conceive, breastfeeding mothers and health professionals. It complements prenatal care: it is not a prescription and does not replace obstetric follow-up or a consultation with a licensed professional.